PrimePCR™ ddPCR™ Expression EvaGreen® Assay: PSMC4, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0011519; Intron-spanning

List Price:    $130.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5017941
Chromosome Location:   19:40480708-40485855question
Amplicon Length:   130

Gene Information

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base which contains 6 ATPase subunits and 2 non-ATPase subunits and a lid which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome the immunoproteasome is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits a member of the triple-A family of ATPases which have a chaperone-like activity. This subunit has been shown to interact with an orphan member of the nuclear hormone receptor superfamily highly expressed in liver and with gankyrin a liver oncoprotein. Two transcript variants encoding different isoforms have been identified. [provided by RefSeq Jul 2008]

Gene Symbol:   PSMC4
Gene Name:   proteasome (prosome, macropain) 26S subunit, ATPase, 4
Aliases:   MGC13687, MGC23214, MGC8570, MIP224, S6, TBP7
RefSeq:   NC_000019.9 NT_011109.16
Ensembl:   ENSG00000013275
Entrez:   5704
UniGene:   Hs.211594
Chromosome Mapping:   19q13.11-q13.13

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