This is the amplicon context sequence in accordance with the minimum information for the publication of real-time quantitative PCR experiements (MIQE) guidelines. For more details, please refer to the following publication, "Primer Sequence Disclosure: A Clarification of the MIQE Guidelines."
ddPCR™ Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.
Info: EG; Same primer pair as used in qPCR assay qHsaCID0011493; Intron-spanning
Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone releasevasoconstriction and increase in blood pressure. Renin an aspartyl protease cleaves angiotensinogen to form angiotensin I which is converted to angiotensin II by angiotensin I converting enzyme an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described but their full-length nature has not been determined. Mutations in this gene have been shown to cause familial hyperproreninemia. [provided by RefSeq Jul 2008]