PrimePCR™ ddPCR™ Expression EvaGreen® Assay: UPF3B, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0011105; Intron-spanning

List Price:    $130.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5017632
Chromosome Location:   X:118985767-118986786question
Amplicon Length:   91

Gene Information

This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. The encoded protein is one of two functional homologs to yeast Upf3p. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export acting as a nucleocytoplasmic shuttling protein. It forms with Y14 a complex that binds specifically 20 nt upstream of exon-exon junctions. This gene is located on the long arm of chromosome X. Two splice variants encoding different isoforms have been found for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   UPF3B
Gene Name:   UPF3 regulator of nonsense transcripts homolog B (yeast)
Aliases:   HUPF3B, MRXS14, RENT3B, UPF3X
RefSeq:   NC_000023.10 NT_011786.16 NG_009241.1
Ensembl:   ENSG00000125351
Entrez:   65109
UniGene:   Hs.103832
Chromosome Mapping:   Xq25-q26

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