PrimePCR™ ddPCR™ Expression EvaGreen® Assay: STAT3, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0010912; Intron-spanning

List Price:    $138.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5017483
Chromosome Location:   17:40469200-40474414question
Amplicon Length:   125

Gene Information

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors STAT family members are phosphorylated by the receptor associated kinases and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs EGF IL5 IL6 HGF LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Three alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq Jul 2008]

Gene Symbol:   STAT3
Gene Name:   signal transducer and activator of transcription 3 (acute-phase response factor)
Aliases:   APRF, FLJ20882, HIES, MGC16063
RefSeq:   NC_000017.10 NT_010783.15 NG_007370.1
Ensembl:   ENSG00000168610
Entrez:   6774
UniGene:   Hs.463059
Chromosome Mapping:   17q21.31

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