PrimePCR™ ddPCR™ Expression EvaGreen® Assay: DCX, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0010869; Intron-spanning

List Price:    $138.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5017451
Chromosome Location:   X:110644488-110653305question
Amplicon Length:   84

Gene Information

This gene encodes a member of the doublecortin family. The protein encoded by this gene is a cytoplasmic protein and contains two doublecortin domains which bind microtubules. In the developing cortex cortical neurons must migrate over long distances to reach the site of their final differentiation. The encoded protein appears to direct neuronal migration by regulating the organization and stability of microtubules. In addition the encoded protein interacts with LIS1 the regulatory gamma subunit of platelet activating factor acetylhydrolase and this interaction is important to proper microtubule function in the developing cortex. Mutations in this gene cause abnormal migration of neurons during development and disrupt the layering of the cortex leading to epilepsy mental retardation subcortical band heterotopia ("double cortex" syndrome) in females and lissencephaly ("smooth brain" syndrome) in males. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Sep 2010]

Gene Symbol:   DCX
Gene Name:   doublecortin
Aliases:   DBCN, DC, FLJ51296, LISX, SCLH, XLIS
RefSeq:   NC_000023.10 NT_011651.17 NG_011750.1
Ensembl:   ENSG00000077279
Entrez:   1641
UniGene:   Hs.34780
Chromosome Mapping:   Xq22.3-q23

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