PrimePCR™ ddPCR™ Expression EvaGreen® Assay: FXYD5, Human

print
PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0010469; Intron-spanning

List Price:    $130.00
Your Price:   Log In
 

Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5017132
Chromosome Location:   19:35646454-35648375question
Amplicon Length:   83

Gene Information

This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Mouse FXYD5 has been termed RIC (Related to Ion Channel). FXYD2 also known as the gamma subunit of the NaK-ATPase regulates the properties of that enzyme. FXYD1 (phospholemman) FXYD2 (gamma) FXYD3 (MAT-8) FXYD4 (CHIF) and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2) with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. This gene product FXYD5 is a glycoprotein that functions in the up-regulation of chemokine production and it is involved in the reduction of cell adhesion via its ability to down-regulate E-cadherin. It also promotes metastasis and has been linked to a variety of cancers. Alternative splicing results in multiple transcript variants. [RefSeq curation by Kathleen J. Sweadner Ph.D. sweadner@helix.mgh.harvard.edu. Sep 2009]

Gene Symbol:   FXYD5
Gene Name:   FXYD domain containing ion transport regulator 5
Aliases:   DYSAD, IWU1, KCT1, OIT2, PRO6241, RIC
RefSeq:   NC_000019.9 NT_011109.16
Ensembl:   ENSG00000089327
Entrez:   53827
UniGene:   Hs.333418
Chromosome Mapping:   19q13.12

Number Description Download
10033487 ddPCR™ Mutation Detection Assays Product Insert, Ver C Click to download
10033173 ddPCR™ Copy Number Variation Assays Product Insert, Ver C Click to download
10041702 PrimePCR™ ddPCR™ Gene Expression Assays (EvaGreen) Product Insert, Rev A Click to download
10047489 ddPCR™ Mutation Detection Assays Product Insert, Ver B Click to download
10048730 PrimePCR™ ddPCR™ Gene Expression Probe Assays Product Insert, Rev A Click to download
Get Help

Call us at 1-800-4-BIORAD (1-800-424-6723)

Sign Up for Bio-Rad Updates!
Enter your email address below to receive your choice of the latest news, promotions, and more.