PrimePCR™ ddPCR™ Expression EvaGreen® Assay: PSMA7, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0010459; Intron-spanning

List Price:    $130.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5017124
Chromosome Location:   20:60712428-60713280question
Amplicon Length:   79

Gene Information

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome the immunoproteasome is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family that is a 20S core alpha subunit. This particular subunit has been shown to interact specifically with the hepatitis B virus X protein a protein critical to viral replication. In addition this subunit is involved in regulating hepatitis virus C internal ribosome entry site (IRES) activity an activity essential for viral replication. This core alpha subunit is also involved in regulating the hypoxia-inducible factor-1alpha a transcription factor important for cellular responses to oxygen tension. Multiple isoforms of this subunit arising from alternative splicing may exist but alternative transcripts for only two isoforms have been defined. A pseudogene has been identified on chromosome 9. [provided by RefSeq Jul 2008]

Gene Symbol:   PSMA7
Gene Name:   proteasome (prosome, macropain) subunit, alpha type, 7
Aliases:   C6, HSPC, MGC3755, RC6-1, XAPC7
RefSeq:   NC_000020.10 NT_011362.10
Ensembl:   ENSG00000101182
Entrez:   5688
UniGene:   Hs.233952
Chromosome Mapping:   20q13.33

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