PrimePCR™ ddPCR™ Expression EvaGreen® Assay: ATRX, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0010314; Intron-spanning

List Price:    $138.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5017003
Chromosome Location:   X:76940448-76944411question
Amplicon Length:   122

Gene Information

The protein encoded by this gene contains an ATPase/helicase domain and thus it belongs to the SWI/SNF family of chromatin remodeling proteins. The mutations of this gene are associated with an X-linked mental retardation (XLMR) syndrome most often accompanied by alpha-thalassemia (ATRX) syndrome. These mutations have been shown to cause diverse changes in the pattern of DNA methylation which may provide a link between chromatin remodeling DNA methylation and gene expression in developmental processes. This protein is found to undergo cell cycle-dependent phosphorylation which regulates its nuclear matrix and chromatin association and suggests its involvement in the gene regulation at interphase and chromosomal segregation in mitosis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq Jul 2008]

Gene Symbol:   ATRX
Gene Name:   alpha thalassemia/mental retardation syndrome X-linked
Aliases:   ATR2, JMS, MGC2094, MRXHF1, RAD54, RAD54L, SFM1, SHS, XH2, XNP, ZNF-HX
RefSeq:   NC_000023.10 NG_008838.1 NT_011651.17
Ensembl:   ENSG00000085224
Entrez:   546
UniGene:   Hs.533526
Chromosome Mapping:   Xq21.1

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