PrimePCR™ ddPCR™ Expression EvaGreen® Assay: DYRK1A, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0010296; Intron-spanning

List Price:    $130.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5016988
Chromosome Location:   21:38865421-38868504question
Amplicon Length:   100

Gene Information

This gene encodes a member of the Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family. This member contains a nuclear targeting signal sequence a protein kinase domain a leucine zipper motif and a highly conservative 13-consecutive-histidine repeat. It catalyzes its autophosphorylation on serine/threonine and tyrosine residues. It may play a significant role in a signaling pathway regulating cell proliferation and may be involved in brain development. This gene is a homolog of Drosophila mnb (minibrain) gene and rat Dyrk gene. It is localized in the Down syndrome critical region of chromosome 21 and is considered to be a strong candidate gene for learning defects associated with Down syndrome. Alternative splicing of this gene generates several transcript variants differing from each other either in the 5' UTR or in the 3' coding region. These variants encode at least five different isoforms. [provided by RefSeq Jul 2008]

Gene Symbol:   DYRK1A
Gene Name:   dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
Aliases:   DYRK, DYRK1, HP86, MNB, MNBH
RefSeq:   NC_000021.8 NT_011512.11 NG_009366.1
Ensembl:   ENSG00000157540
Entrez:   1859
UniGene:   Hs.368240
Chromosome Mapping:   21q22.13

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