PrimePCR™ ddPCR™ Expression EvaGreen® Assay: NARF, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0009849; Intron-spanning

List Price:    $130.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5016669
Chromosome Location:   17:80443438-80445859question
Amplicon Length:   131

Gene Information

Several proteins have been found to be prenylated and methylated at their carboxyl-terminal ends. Prenylation was initially believed to be important only for membrane attachment. However another role for prenylation appears to be its importance in protein-protein interactions. The only nuclear proteins known to be prenylated in mammalian cells are prelamin A- and B-type lamins. Prelamin A is farnesylated and carboxymethylated on the cysteine residue of a carboxyl-terminal CaaX motif. This post-translationally modified cysteine residue is removed from prelamin A when it is endoproteolytically processed into mature lamin A. The protein encoded by this gene binds to the prenylated prelamin A carboxyl-terminal tail domain. It may be a component of a prelamin A endoprotease complex. The encoded protein is located in the nucleus where it partially colocalizes with the nuclear lamina. It shares limited sequence similarity with iron-only bacterial hydrogenases. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene including one with a novel exon that is generated by RNA editing. [provided by RefSeq Jul 2008]

Gene Symbol:   NARF
Gene Name:   nuclear prelamin A recognition factor
Aliases:   DKFZp434G0420, FLJ10067, IOP2
RefSeq:   NC_000017.10 NT_010663.15
Ensembl:   ENSG00000141562
Entrez:   26502
UniGene:   Hs.256526
Chromosome Mapping:   17q25.3

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