PrimePCR™ ddPCR™ Expression EvaGreen® Assay: ATF1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0009625; Intron-spanning

List Price:    $130.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5016525
Chromosome Location:   12:51203303-51207852question
Amplicon Length:   100

Gene Information

This gene encodes an activating transcription factor which belongs to the ATF subfamily and bZIP (basic-region leucine zipper) family. It influences cellular physiologic processes by regulating the expression of downstream target genes which are related to growth survival and other cellular activities. This protein is phosphorylated at serine 63 in its kinase-inducible domain by serine/threonine kinases cAMP-dependent protein kinase A calmodulin-dependent protein kinase I/II mitogen- and stress-activated protein kinase and cyclin-dependent kinase 3 (cdk-3). Its phosphorylation enhances its transactivation and transcriptional activities and enhances cell transformation. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in angiomatoid fibrous histiocytoma and clear cell sarcoma. This gene has a pseudogene on chromosome 6. [provided by RefSeq Aug 2010]

Gene Symbol:   ATF1
Gene Name:   activating transcription factor 1
Aliases:   EWS-ATF1, FUS/ATF-1, TREB36
RefSeq:   NC_000012.11 NG_027673.1 NT_029419.12
Ensembl:   ENSG00000123268
Entrez:   466
UniGene:   Hs.648565
Chromosome Mapping:   12q13

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