PrimePCR™ ddPCR™ Expression EvaGreen® Assay: ALOX5, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0006575; Intron-spanning

List Price:    $138.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5014568
Chromosome Location:   10:45869760-45877965question
Amplicon Length:   123

Gene Information

This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein which is expressed specifically in bone marrow-derived cells catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-81114-cis-eicosatetraenoic acid and further to the allylic epoxide 5(S)-trans-79-trans-1114-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Jan 2012]

Gene Symbol:   ALOX5
Gene Name:   arachidonate 5-lipoxygenase
Aliases:   5-LO, 5-LOX, 5LPG, LOG5, MGC163204
RefSeq:   NC_000010.10 NG_011437.1 NT_033985.7 NW_003315935.1
Ensembl:   ENSG00000012779
Entrez:   240
UniGene:   Hs.89499
Chromosome Mapping:   10q11.2

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