PrimePCR™ ddPCR™ Expression EvaGreen® Assay: MBD3, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0006534; Intron-spanning

List Price:    $130.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5014534
Chromosome Location:   19:1582657-1584620question
Amplicon Length:   107

Gene Information

DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2 MBD1 MBD2 MBD3 and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). However unlike the other family members MBD3 is not capable of binding to methylated DNA. The predicted MBD3 protein shares 71% and 94% identity with MBD2 (isoform 1) and mouse Mbd3. MBD3 is a subunit of the NuRD a multisubunit complex containing nucleosome remodeling and histone deacetylase activities. MBD3 mediates the association of metastasis-associated protein 2 (MTA2) with the core histone deacetylase complex. [provided by RefSeq Jul 2008]

Gene Symbol:   MBD3
Gene Name:   methyl-CpG binding domain protein 3
Aliases:   Not Available
RefSeq:   NC_000019.9 NT_011255.14
Ensembl:   ENSG00000071655
Entrez:   53615
UniGene:   Hs.178728
Chromosome Mapping:   19p13.3

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