PrimePCR™ ddPCR™ Expression EvaGreen® Assay: ARID1A, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0006352; Intron-spanning

List Price:    $130.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5014398
Chromosome Location:   1:27097744-27099059question
Amplicon Length:   113

Gene Information

This gene encodes a member of the SWI/SNF family whose members have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI which is required for transcriptional activation of genes normally repressed by chromatin. It possesses at least two conserved domains that could be important for its function. First it has a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus. Second the C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation. It is thought that the protein encoded by this gene confers specificity to the SNF/SWI complex and may recruit the complex to its targets through either protein-DNA or protein-protein interactions. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   ARID1A
Gene Name:   AT rich interactive domain 1A (SWI-like)
Aliases:   B120, BAF250, BAF250a, BM029, C1orf4, P270, SMARCF1
RefSeq:   NC_000001.10 NT_004610.19
Ensembl:   ENSG00000117713
Entrez:   8289
UniGene:   Hs.468972
Chromosome Mapping:   1p35.3

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