This is the amplicon context sequence in accordance with the minimum information for the publication of real-time quantitative PCR experiements (MIQE) guidelines. For more details, please refer to the following publication, "Primer Sequence Disclosure: A Clarification of the MIQE Guidelines."
ddPCR™ Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.
Info: EG; Same primer pair as used in qPCR assay qHsaCID0006233; Intron-spanning
ITAGV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains that combine with multiple integrin beta chains to form different integrins. Among the known associating beta chains (beta chains 1356 and 8; 'ITGB1' 'ITGB3' 'ITGB5' 'ITGB6' and 'ITGB8') each can interact with extracellular matrix ligands; the alpha V beta 3 integrin perhaps the most studied of these is referred to as the Vitronectin receptor (VNR). In addition to adhesion many integrins are known to facilitate signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq Feb 2009]