PrimePCR™ ddPCR™ Expression EvaGreen® Assay: ANTXR1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0006028; Intron-spanning

List Price:    $130.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5014133
Chromosome Location:   2:69330043-69351703question
Amplicon Length:   76

Gene Information

This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin the causative agent of the disease anthrax. The binding of the protective antigen (PA) component of the tripartite anthrax toxin to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell the other two components of anthrax toxin edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described. [provided by RefSeq Oct 2008]

Gene Symbol:   ANTXR1
Gene Name:   anthrax toxin receptor 1
Aliases:   ATR, FLJ10601, FLJ11298, FLJ21776, TEM8
RefSeq:   NC_000002.11 NT_022184.15 NG_012649.1
Ensembl:   ENSG00000169604
Entrez:   84168
UniGene:   Hs.165859
Chromosome Mapping:   2p13.1

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