PrimePCR™ ddPCR™ Expression EvaGreen® Assay: APP, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0057336; exonic

List Price:    $138.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5013883
Chromosome Location:   21:27327987-27347407question
Amplicon Length:   78

Gene Information

This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   APP
Gene Name:   amyloid beta (A4) precursor protein
Aliases:   AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN2
RefSeq:   NC_000021.8 NG_007376.1 NT_011512.11
Ensembl:   ENSG00000142192
Entrez:   351
UniGene:   Hs.434980
Chromosome Mapping:   21q21.2,21q21.3

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