PrimePCR™ ddPCR™ Expression EvaGreen® Assay: NLRP11, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0056942; exonic

List Price:    $138.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5013532
Chromosome Location:   19:56320703-56320849question
Amplicon Length:   117

Gene Information

NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs such as NALP11 have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD) followed by a NACHT domain a NACHT-associated domain (NAD) and a C-terminal leucine-rich repeat (LRR) region. The long NALP NALP1 (MIM 606636) also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g. CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al. 2003 [PubMed 12563287]).[supplied by OMIM Mar 2008]

Gene Symbol:   NLRP11
Gene Name:   NLR family, pyrin domain containing 11
Aliases:   CLR19.6, FLJ26273, NALP11, NOD17, PAN10, PYPAF6, PYPAF7
RefSeq:   NC_000019.9 NT_011109.16
Ensembl:   ENSG00000179873
Entrez:   204801
UniGene:   Hs.375039
Chromosome Mapping:   19q13.43

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