PrimePCR™ ddPCR™ Expression EvaGreen® Assay: CARD8, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0056873; exonic

List Price:    $130.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5013474
Chromosome Location:   19:48714882-48714985question
Amplicon Length:   74

Gene Information

The protein encoded by this gene belongs to the caspase recruitment domain (CARD)-containing family of proteins which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation CASP1-dependent IL1B secretion and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq May 2010]

Gene Symbol:   CARD8
Gene Name:   caspase recruitment domain family, member 8
Aliases:   CARDINAL, DACAR, DAKAR, DKFZp779L0366, FLJ18119, FLJ18121, KIAA0955, MGC57162, NDPP, NDPP1, TUCAN
RefSeq:   NC_000019.9 NT_011109.16
Ensembl:   ENSG00000105483
Entrez:   22900
UniGene:   Hs.446146
Chromosome Mapping:   19q13.33

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