PrimePCR™ ddPCR™ Expression EvaGreen® Assay: TCF3, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0056845; exonic

List Price:    $130.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5013457
Chromosome Location:   19:1609746-1609875question
Amplicon Length:   100

Gene Information

This gene encodes a member of the E protein (class I) family of helix-loop-helix transcription factors. E proteins activate transcription by binding to regulatory E-box sequences on target genes as heterodimers or homodimers and are inhibited by heterodimerization with inhibitor of DNA-binding (class IV) helix-loop-helix proteins. E proteins play a critical role in lymphopoiesis and the encoded protein is required for B and T lymphocyte development. Deletion of this gene or diminished activity of the encoded protein may play a role in lymphoid malignancies. This gene is also involved in several chromosomal translocations that are associated with lymphoid malignancies including pre-B-cell acute lymphoblastic leukemia (t(1;19) with PBX1) childhood leukemia (t(19;19) with TFPT) and acute leukemia (t(12;19) with ZNF384). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene and a pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq Sep 2011]

Gene Symbol:   TCF3
Gene Name:   transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)
Aliases:   E2A, ITF1, MGC129647, MGC129648, VDIR, bHLHb21
RefSeq:   NC_000019.9 NT_011255.14
Ensembl:   ENSG00000071564
Entrez:   6929
UniGene:   Hs.371282
Chromosome Mapping:   19p13.3

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