PrimePCR™ ddPCR™ Expression EvaGreen® Assay: IL7R, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0056514; exonic

List Price:    $130.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5013203
Chromosome Location:   5:35876996-35877145question
Amplicon Length:   120

Gene Information

The protein encoded by this gene is a receptor for interleukine 7 (IL7). The function of this receptor requires the interleukin 2 receptor gamma chain (IL2RG) which is a common gamma chain shared by the receptors of various cytokines including interleukine 2 4 7 9 and 15. This protein has been shown to play a critical role in the V(D)J recombination during lymphocyte development. This protein is also found to control the accessibility of the TCR gamma locus by STAT5 and histone acetylation. Knockout studies in mice suggested that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. The functional defects in this protein may be associated with the pathogenesis of the severe combined immunodeficiency (SCID). [provided by RefSeq Jul 2008]

Gene Symbol:   IL7R
Gene Name:   interleukin 7 receptor
Aliases:   CD127, CDW127, IL-7R-alpha, IL7RA, ILRA
RefSeq:   NC_000005.9 NG_009567.1 NT_006576.16
Ensembl:   ENSG00000168685
Entrez:   3575
UniGene:   Hs.591742
Chromosome Mapping:   5p13

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