PrimePCR™ ddPCR™ Expression EvaGreen® Assay: SFTPB, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0046584; exonic

List Price:    $138.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5011015
Chromosome Location:   2:85894295-85894898question
Amplicon Length:   73

Gene Information

This gene encodes the pulmonary-associated surfactant protein B (SPB) an amphipathic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA SPB SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. The SPB enhances the rate of spreading and increases the stability of surfactant monolayers in vitro. Multiple mutations in this gene have been identified which cause pulmonary surfactant metabolism dysfunction type 1 also called pulmonary alveolar proteinosis due to surfactant protein B deficiency and are associated with fatal respiratory distress in the neonatal period. Alternatively spliced transcript variants encoding the same protein have been identified.[provided by RefSeq Feb 2010]

Gene Symbol:   SFTPB
Gene Name:   surfactant protein B
Aliases:   PSP-B, SFTB3, SFTP3, SMDP1, SP-B
RefSeq:   NC_000002.11 NT_022184.15 NG_016967.1
Ensembl:   ENSG00000168878
Entrez:   6439
UniGene:   Hs.512690
Chromosome Mapping:   2p12-p11.2

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