This is the amplicon context sequence in accordance with the minimum information for the publication of real-time quantitative PCR experiements (MIQE) guidelines. For more details, please refer to the following publication, "Primer Sequence Disclosure: A Clarification of the MIQE Guidelines."
ddPCR™ Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.
Info: EG; Same primer pair as used in qPCR assay qHsaCED0045832; exonic
This gene encodes a protein that contains a death effector domain (DED). DED is a protein-protein interaction domain shared by adaptors regulators and executors of the programmed cell death pathway. Overexpression of this gene was shown to induce weak apoptosis. Upon stimulation this protein was found to translocate from cytoplasm to nucleus and colocalize with UBTF a basal factor required for RNA polymerase I transcription in the nucleolus. At least three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq Jul 2008]