This is the amplicon context sequence in accordance with the minimum information for the publication of real-time quantitative PCR experiements (MIQE) guidelines. For more details, please refer to the following publication, "Primer Sequence Disclosure: A Clarification of the MIQE Guidelines."
ddPCR™ Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.
Info: EG; Same primer pair as used in qPCR assay qHsaCED0045651; exonic
This gene encodes a component of the nucleotide excision repair (NER) pathway. There are multiple components involved in the NER pathway including Xeroderma pigmentosum (XP) A-G and V Cockayne syndrome (CS) A and B and trichothiodystrophy (TTD) group A etc. This component XPC plays an important role in the early steps of global genome NER especially in damage recognition open complex formation and repair protein complex formation. Mutations in this gene or some other NER components result in Xeroderma pigmentosum a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq Mar 2009]