PrimePCR™ ddPCR™ Expression EvaGreen® Assay: OPTN, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0043980; exonic

List Price:    $138.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5008683
Chromosome Location:   10:13160908-13161019question
Amplicon Length:   82

Gene Information

This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking vesicle trafficking and transcription activation through its interactions with the RAB8 huntingtin and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq Jul 2008]

Gene Symbol:   OPTN
Gene Name:   optineurin
RefSeq:   NC_000010.10 NG_012876.1 NT_008705.16
Ensembl:   ENSG00000123240
Entrez:   10133
UniGene:   Hs.332706
Chromosome Mapping:   10p13

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