PrimePCR™ ddPCR™ Expression EvaGreen® Assay: APAF1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0043883; exonic

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5008592
Chromosome Location:   12:99042458-99042575question
Amplicon Length:   88

Gene Information

This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain a caspase recruitment domain (CARD) and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein releasing its mature activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq Jul 2008]

Gene Symbol:   APAF1
Gene Name:   apoptotic peptidase activating factor 1
Aliases:   APAF-1, CED4, DKFZp781B1145
RefSeq:   NC_000012.11 NT_029419.12
Ensembl:   ENSG00000120868
Entrez:   317
UniGene:   Hs.552567
Chromosome Mapping:   12q23

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