PrimePCR™ ddPCR™ Expression EvaGreen® Assay: BCCIP, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0043204; exonic

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5008002
Chromosome Location:   10:127520025-127520144question
Amplicon Length:   90

Gene Information

This gene product was isolated on the basis of its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple interacting domains. The N-terminal half shares moderate homology with regions of calmodulin and M-calpain suggesting that it may also bind calcium. Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression and a modulator of CDK2 kinase activity via p21. This protein has also been implicated in the regulation of BRCA2 and RAD51 nuclear focus formation double-strand break-induced homologous recombination and cell cycle progression. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   BCCIP
Gene Name:   BRCA2 and CDKN1A interacting protein
Aliases:   TOK-1, TOK1
RefSeq:   NC_000010.10 NG_011557.1 NT_030059.13
Ensembl:   ENSG00000107949
Entrez:   56647
UniGene:   Hs.715543
Chromosome Mapping:   10q26.1

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