PrimePCR™ ddPCR™ Expression EvaGreen® Assay: MAN2B1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0043028; exonic

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5007854
Chromosome Location:   19:12774568-12775629question
Amplicon Length:   76

Gene Information

This gene encodes an enzyme that hydrolyzes terminal non-reducing alpha-D-mannose residues in alpha-D-mannosides. Its activity is necessary for the catabolism of N-linked carbohydrates released during glycoprotein turnover and it is member of family 38 of glycosyl hydrolases. The full length protein is processed in two steps. First a 49 aa leader sequence is cleaved off and the remainder of the protein is processed into 3 peptides of 70 kDa 42 kDa (D) and 13/15 kDa (E). Next the 70 kDa peptide is further processed into three peptides (A B and C). The A B and C peptides are disulfide-linked. Defects in this gene have been associated with lysosomal alpha-mannosidosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq Mar 2010]

Gene Symbol:   MAN2B1
Gene Name:   mannosidase, alpha, class 2B, member 1
Aliases:   LAMAN, MANB
RefSeq:   NC_000019.9 NG_008318.1 NG_015814.1 NT_011295.11
Ensembl:   ENSG00000104774
Entrez:   4125
UniGene:   Hs.356769
Chromosome Mapping:   19cen-q13.1

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