PrimePCR™ ddPCR™ Expression EvaGreen® Assay: RP1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0042998; exonic

List Price:    $138.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5007826
Chromosome Location:   8:55540292-55540413question
Amplicon Length:   92

Gene Information

This gene encodes a member of the doublecortin family. The protein encoded by this gene contains two doublecortin domains which bind microtubules and regulate microtubule polymerization. The encoded protein is a photoreceptor microtubule-associated protein and is required for correct stacking of outer segment disc. This protein and the RP1L1 protein another retinal-specific protein play essential and synergistic roles in affecting photosensitivity and outer segment morphogenesis of rod photoreceptors. Because of its response to in vivo retinal oxygen levels this protein was initially named ORP1 (oxygen-regulated protein-1). This protein was subsequently designated RP1 (retinitis pigmentosa 1) when it was found that mutations in this gene cause autosomal dominant retinitis pigmentosa. Mutations in this gene also cause autosomal recessive retinitis pigmentosa. Transcript variants resulted from an alternative promoter and alternative splicings have been found which overlap the current reference sequence and has several exons upstream and downstream of the current reference sequence. However the biological validity and full-length nature of some variants cannot be determined at this time.[provided by RefSeq Sep 2010]

Gene Symbol:   RP1
Gene Name:   retinitis pigmentosa 1 (autosomal dominant)
Aliases:   DCDC4A, FLJ50293, FLJ55454, FLJ79410, ORP1
RefSeq:   NC_000008.10 NG_009840.1 NT_008183.19
Ensembl:   ENSG00000104237
Entrez:   6101
UniGene:   Hs.732820
Chromosome Mapping:   8q12.1

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