PrimePCR™ ddPCR™ Expression EvaGreen® Assay: E2F1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0042864; exonic

List Price:    $138.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5007705
Chromosome Location:   20:32263794-32263900question
Amplicon Length:   77

Gene Information

The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP) a transactivation domain enriched in acidic amino acids and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members E2F2 and E2F3 have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis. [provided by RefSeq Jul 2008]

Gene Symbol:   E2F1
Gene Name:   E2F transcription factor 1
Aliases:   E2F-1, RBAP1, RBBP3, RBP3
RefSeq:   NC_000020.10 NT_011362.10
Ensembl:   ENSG00000101412
Entrez:   1869
UniGene:   Hs.654393
Chromosome Mapping:   20q11.2

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