This is the amplicon context sequence in accordance with the minimum information for the publication of real-time quantitative PCR experiements (MIQE) guidelines. For more details, please refer to the following publication, "Primer Sequence Disclosure: A Clarification of the MIQE Guidelines."
ddPCR™ Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.
Info: EG; Same primer pair as used in qPCR assay qHsaCED0042641; exonic
This gene encodes an estrogen receptor a ligand-activated transcription factor composed of several domains important for hormone binding DNA binding and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer endometrial cancer and osteoporosis. Alternative splicing results in several transcript variants which differ in their 5' UTRs and use different promoters. [provided by RefSeq Jul 2008]