PrimePCR™ ddPCR™ Expression EvaGreen® Assay: NLRC4, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0042623; exonic

List Price:    $130.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5007476
Chromosome Location:   2:32449542-32449640question
Amplicon Length:   69

Gene Information

In C. elegans Ced4 binds and activates Ced3 an apoptotic initiator caspase via caspase-associated recruitment domains (CARDs). Human Ced4 homologs include APAF1 (MIM 602233) NOD1/CARD4 (MIM 605980) and NOD2/CARD15 (MIM 605956). These proteins have at least 1 N-terminal CARD domain followed by a centrally located nucleotide-binding domain (NBD or NACHT) and a C-terminal regulatory domain found only in mammals that contains either WD40 repeats or leucine-rich repeats (LRRs). CARD12 is a member of the Ced4 family and can induce apoptosis.[supplied by OMIM Mar 2008]

Gene Symbol:   NLRC4
Gene Name:   NLR family, CARD domain containing 4
Aliases:   CARD12, CLAN, CLAN1, CLANA, CLANB, CLANC, CLAND, CLR2.1, IPAF
RefSeq:   NC_000002.11 NT_022184.15
Ensembl:   ENSG00000091106
Entrez:   58484
UniGene:   Hs.574741
Chromosome Mapping:   2p22-p21

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