PrimePCR™ ddPCR™ Expression EvaGreen® Assay: F11, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0042586; exonic

List Price:    $130.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5007445
Chromosome Location:   4:187206834-187206966question
Amplicon Length:   103

Gene Information

This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains resulting in activated factor XIa a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome a blood coagulation abnormality. [provided by RefSeq Jul 2008]

Gene Symbol:   F11
Gene Name:   coagulation factor XI
Aliases:   FXI, MGC141891
RefSeq:   NC_000004.11 NG_008051.1 NT_016354.19
Ensembl:   ENSG00000088926
Entrez:   2160
UniGene:   Hs.1430
Chromosome Mapping:   4q35

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10033487 ddPCR™ Mutation Detection Assays Product Insert, Ver C Click to download
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10041702 PrimePCR™ ddPCR™ Gene Expression Assays (EvaGreen) Product Insert, Rev A Click to download
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