PrimePCR™ ddPCR™ Expression EvaGreen® Assay: STRADB, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0042478; exonic

List Price:    $130.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5007380
Chromosome Location:   2:202344986-202345133question
Amplicon Length:   118

Gene Information

This gene encodes a protein that belongs to the serine/threonine protein kinase STE20 subfamily. One of the active site residues in the protein kinase domain of this protein is altered and it is thus a pseudokinase. This protein is a component of a complex involved in the activation of serine/threonine kinase 11 a master kinase that regulates cell polarity and energy-generating metabolism. This complex regulates the relocation of this kinase from the nucleus to the cytoplasm and it is essential for G1 cell cycle arrest mediated by this kinase. The protein encoded by this gene can also interact with the X chromosome-linked inhibitor of apoptosis protein and this interaction enhances the anti-apoptotic activity of this protein via the JNK1 signal transduction pathway. Two pseudogenes located on chromosomes 1 and 7 have been found for this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq May 2011]

Gene Symbol:   STRADB
Gene Name:   STE20-related kinase adaptor beta
Aliases:   ALS2CR2, CALS-21, ILPIP, ILPIPA, MGC102916, PAPK
RefSeq:   NC_000002.11 NT_005403.17
Ensembl:   ENSG00000082146
Entrez:   55437
UniGene:   Hs.652338
Chromosome Mapping:   2q33.1

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