PrimePCR™ ddPCR™ Expression EvaGreen® Assay: FGFR1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0042405; exonic

List Price:    $130.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5007339
Chromosome Location:   8:38282049-38282154question
Amplicon Length:   76

Gene Information

The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region composed of three immunoglobulin-like domains a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors setting in motion a cascade of downstream signals ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene have been associated with Pfeiffer syndrome Jackson-Weiss syndrome Antley-Bixler syndrome osteoglophonic dysplasia and autosomal dominant Kallmann syndrome 2. Chromosomal aberrations involving this gene are associated with stem cell myeloproliferative disorder and stem cell leukemia lymphoma syndrome. Alternatively spliced variants which encode different protein isoforms have been described; however not all variants have been fully characterized. [provided by RefSeq Jul 2008]

Gene Symbol:   FGFR1
Gene Name:   fibroblast growth factor receptor 1
Aliases:   BFGFR, CD331, CEK, FGFBR, FGFR-1, FLG, FLJ99988, FLT-2, FLT2, HBGFR, KAL2, N-SAM, OGD, bFGF-R-1
RefSeq:   NC_000008.10 NT_167187.1 NG_007729.1
Ensembl:   ENSG00000077782
Entrez:   2260
UniGene:   Hs.264887
Chromosome Mapping:   8p12

Number Description Download
10033487 ddPCR™ Mutation Detection Assays Product Insert, Ver C Click to download
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10041702 PrimePCR™ ddPCR™ Gene Expression Assays (EvaGreen) Product Insert, Rev A Click to download
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