PrimePCR™ ddPCR™ Expression EvaGreen® Assay: ING3, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0042306; exonic

List Price:    $130.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5007249
Chromosome Location:   7:120590881-120591235question
Amplicon Length:   86

Gene Information

The protein encoded by this gene is similar to ING1 a tumor suppressor protein that can interact with TP53 inhibit cell growth and induce apoptosis. This protein contains a PHD-finger which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters including promoters of p21/waf1 and bax. Overexpression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers. Two alternatively spliced transcript variants encoding different isoforms have been observed. [provided by RefSeq Jul 2008]

Gene Symbol:   ING3
Gene Name:   inhibitor of growth family, member 3
Aliases:   Eaf4, FLJ20089, ING2, MEAF4, p47ING3
RefSeq:   NC_000007.13 NG_023322.1 NT_007933.15
Ensembl:   ENSG00000071243
Entrez:   54556
UniGene:   Hs.489811
Chromosome Mapping:   7q31

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