PrimePCR™ ddPCR™ Expression EvaGreen® Assay: RFXANK, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0042209; exonic

List Price:    $138.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5007162
Chromosome Location:   19:19303348-19303885question
Amplicon Length:   103

Gene Information

Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene along with regulatory factor X-associated protein and regulatory factor-5 forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter this complex associates with the non-DNA-binding factor MHC class II transactivator which controls the cell type specificity and inducibility of MHC class II gene expression. This protein contains ankyrin repeats involved in protein-protein interactions. Mutations in this gene have been linked to bare lymphocyte syndrome type II complementation group B. Two transcript variants encoding different isoforms have been described for this gene with only one isoform showing activation activity. [provided by RefSeq Jul 2008]

Gene Symbol:   RFXANK
Gene Name:   regulatory factor X-associated ankyrin-containing protein
Aliases:   ANKRA1, BLS, F14150_1, MGC138628, RFX-B
RefSeq:   NC_000019.9 NG_007432.1 NT_011295.11
Ensembl:   ENSG00000064490
Entrez:   8625
UniGene:   Hs.296776
Chromosome Mapping:   19p12

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