PrimePCR™ ddPCR™ Expression EvaGreen® Assay: HERPUD1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0042132; exonic

List Price:    $130.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5007092
Chromosome Location:   16:56973179-56973812question
Amplicon Length:   69

Gene Information

The accumulation of unfolded proteins in the endoplasmic reticulum (ER) triggers the ER stress response. This response includes the inhibition of translation to prevent further accumulation of unfolded proteins the increased expression of proteins involved in polypeptide folding known as the unfolded protein response (UPR) and the destruction of misfolded proteins by the ER-associated protein degradation (ERAD) system. This gene may play a role in both UPR and ERAD. Its expression is induced by UPR and it has an ER stress response element in its promoter region while the encoded protein has an N-terminal ubiquitin-like domain which may interact with the ERAD system. This protein has been shown to interact with presenilin proteins and to increase the level of amyloid-beta protein following its overexpression. Alternative splicing of this gene produces multiple transcript variants some encoding different isoforms. The full-length nature of all transcript variants has not been determined. [provided by RefSeq Jul 2008]

Gene Symbol:   HERPUD1
Gene Name:   homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
Aliases:   HERP, KIAA0025, Mif1, SUP
RefSeq:   NC_000016.9 NT_010498.15
Ensembl:   ENSG00000051108
Entrez:   9709
UniGene:   Hs.146393
Chromosome Mapping:   16q13

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