PrimePCR™ ddPCR™ Expression EvaGreen® Assay: HEXB, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0042124; exonic

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5007084
Chromosome Location:   5:74016338-74016567question
Amplicon Length:   76

Gene Information

Hexosaminidase B is the beta subunit of the lysosomal enzyme beta-hexosaminidase that together with the cofactor GM2 activator protein catalyzes the degradation of the ganglioside GM2 and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits alpha and beta which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Beta subunit gene mutations lead to Sandhoff disease (GM2-gangliosidosis type II). [provided by RefSeq Jul 2008]

Gene Symbol:   HEXB
Gene Name:   hexosaminidase B (beta polypeptide)
Aliases:   ENC-1AS
RefSeq:   NC_000005.9 NG_009770.1 NG_011531.1 NT_006713.15
Ensembl:   ENSG00000049860
Entrez:   3074
UniGene:   Hs.69293
Chromosome Mapping:   5q13

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