PrimePCR™ ddPCR™ Expression EvaGreen® Assay: RNF19A, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0042057; exonic

List Price:    $130.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5007021
Chromosome Location:   8:101300188-101300336question
Amplicon Length:   119

Gene Information

The protein encoded by this gene contains two RING-finger motifs and an IBR (in between RING fingers) motif. This protein is an E3 ubiquitin ligase that is localized in Lewy bodies a characteristic neuronal inclusion in Parkinson's disease (PD) brains. This protein interacts with UBE2L3/UBCH7 and UBE2E2/UBCH8 but not other ubiquitin-conjugating enzymes. This protein binds and ubiquitylates synphilin 1 (SNCAIP) which is an interacting protein of alpha synuclein in neurons and a major component of Lewy bodies. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq Feb 2012]

Gene Symbol:   RNF19A
Gene Name:   ring finger protein 19A
Aliases:   DKFZp566B1346, DORFIN, RNF19
RefSeq:   NC_000008.10 NT_008046.16
Ensembl:   ENSG00000034677
Entrez:   25897
UniGene:   Hs.292882
Chromosome Mapping:   8q22

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