PrimePCR™ ddPCR™ Expression EvaGreen® Assay: TYROBP, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0041980; exonic

List Price:    $130.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5006951
Chromosome Location:   19:36395366-36395456question
Amplicon Length:   61

Gene Information

This gene encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. This protein may bind zeta-chain (TCR) associated protein kinase 70kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction bone modeling brain myelination and inflammation. Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL) also known as Nasu-Hakola disease. Its putative receptor triggering receptor expressed on myeloid cells 2 (TREM2) also causes PLOSL. Multiple alternative transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq Mar 2010]

Gene Symbol:   TYROBP
Gene Name:   TYRO protein tyrosine kinase binding protein
Aliases:   DAP12, KARAP, PLOSL
RefSeq:   NC_000019.9 NT_011109.16 NG_009304.1
Ensembl:   ENSG00000011600
Entrez:   7305
UniGene:   Hs.515369
Chromosome Mapping:   19q13.1

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