PrimePCR™ ddPCR™ Expression EvaGreen® Assay: MMP25, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0041950; exonic

List Price:    $130.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5006927
Chromosome Location:   16:3110524-3110647question
Amplicon Length:   94

Gene Information

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes such as embryonic development reproduction and tissue remodeling as well as in disease processes such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily attached to the plasma membrane via a glycosylphosphatidyl inositol anchor. In response to bacterial infection or inflammation the encoded protein is thought to inactivate alpha-1 proteinase inhibitor a major tissue protectant against proteolytic enzymes released by activated neutrophils facilitating the transendothelial migration of neutrophils to inflammatory sites. The encoded protein may also play a role in tumor invasion and metastasis through activation of MMP2. The gene has previously been referred to as MMP20 but has been renamed MMP25. [provided by RefSeq Jul 2008]

Gene Symbol:   MMP25
Gene Name:   matrix metallopeptidase 25
Aliases:   MMP-25, MMP20, MMP20A, MMPL1, MT-MMP 6, MT-MMP6, MT6-MMP, MT6MMP, MTMMP6
RefSeq:   NC_000016.9 NT_010393.16
Ensembl:   ENSG00000008516
Entrez:   64386
UniGene:   Hs.654979
Chromosome Mapping:   16p13.3

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