PrimePCR™ ddPCR™ Expression EvaGreen® Assay: COX10, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0041926; exonic

List Price:    $130.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5006907
Chromosome Location:   17:13977696-13980078question
Amplicon Length:   75

Gene Information

Cytochrome c oxidase (COX) the terminal component of the mitochondrial respiratory chain catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes heme A:farnesyltransferase which is not a structural subunit but required for the expression of functional COX and functions in the maturation of the heme A prosthetic group of COX. This protein is predicted to contain 7-9 transmembrane domains localized in the mitochondrial inner membrane. A gene mutation which results in the substitution of a lysine for an asparagine (N204K) is identified to be responsible for cytochrome c oxidase deficiency. In addition this gene is disrupted in patients with CMT1A (Charcot-Marie-Tooth type 1A) duplication and with HNPP (hereditary neuropathy with liability to pressure palsies) deletion. [provided by RefSeq Jul 2008]

Gene Symbol:   COX10
Gene Name:   COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase (yeast)
Aliases:   Not Available
RefSeq:   NC_000017.10 NG_008034.1 NT_010718.16
Ensembl:   ENSG00000006695
Entrez:   1352
UniGene:   Hs.462278
Chromosome Mapping:   17p12

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