PrimePCR™ ddPCR™ Expression EvaGreen® Assay: CDC27, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0041891; exonic

List Price:    $130.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5006877
Chromosome Location:   17:45198237-45199810question
Amplicon Length:   118

Gene Information

The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae protein Cdc27 and the gene product of Schizosaccharomyces pombe nuc 2. This protein is a component of anaphase-promoting complex (APC) which is composed of eight protein subunits and highly conserved in eucaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat) a protein domain important for protein-protein interaction. This protein was shown to interact with mitotic checkpoint proteins including Mad2 p55CDC and BUBR1 and thus may be involved in controlling the timing of mitosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   CDC27
Gene Name:   cell division cycle 27 homolog (S. cerevisiae)
Aliases:   ANAPC3, APC3, CDC27Hs, D0S1430E, D17S978E, HNUC, NUC2
RefSeq:   NC_000017.10 NT_010783.15
Ensembl:   ENSG00000004897
Entrez:   996
UniGene:   Hs.463295
Chromosome Mapping:   17q21.32

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