PrimePCR™ ddPCR™ Expression EvaGreen® Assay: CYP2B6, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0038976; exonic

List Price:    $130.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5006797
Chromosome Location:   19:41522867-41523086question
Amplicon Length:   190

Gene Information

This gene CYP2B6 encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize some xenobiotics such as the anti-cancer drugs cyclophosphamide and ifosphamide. Transcript variants for this gene have been described; however it has not been resolved whether these transcripts are in fact produced by this gene or by a closely related pseudogene CYP2B7. Both the gene and the pseudogene are located in the middle of a CYP2A pseudogene found in a large cluster of cytochrome P450 genes from the CYP2A CYP2B and CYP2F subfamilies on chromosome 19q. [provided by RefSeq Jul 2008]

Gene Symbol:   CYP2B6
Gene Name:   cytochrome P450, family 2, subfamily B, polypeptide 6
Aliases:   CPB6, CYP2B, CYP2B7, CYP2B7P, CYPIIB6, IIB1, P450
RefSeq:   NC_000019.9 NG_000008.7 NG_007929.1 NT_011109.16
Ensembl:   ENSG00000197408
Entrez:   1555
UniGene:   Hs.1360
Chromosome Mapping:   19q13.2

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