PrimePCR™ ddPCR™ Expression EvaGreen® Assay: APBB1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0038941; exonic

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5006773
Chromosome Location:   11:6424940-6425045question
Amplicon Length:   76

Gene Information

The protein encoded by this gene is a member of the Fe65 protein family. It is an adaptor protein localized in the nucleus. It interacts with the Alzheimer's disease amyloid precursor protein (APP) transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein. APP functions as a cytosolic anchoring site that can prevent the gene product's nuclear translocation. This encoded protein could play an important role in the pathogenesis of Alzheimer's disease. It is thought to regulate transcription. Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq Mar 2012]

Gene Symbol:   APBB1
Gene Name:   amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
Aliases:   FE65, MGC:9072, RIR
RefSeq:   NC_000011.9 NG_011780.1 NT_009237.18
Ensembl:   ENSG00000166313
Entrez:   322
UniGene:   Hs.372840
Chromosome Mapping:   11p15

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