PrimePCR™ ddPCR™ Expression EvaGreen® Assay: PTPRC, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0038908; exonic

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5006749
Chromosome Location:   1:198608356-198608454question
Amplicon Length:   69

Gene Information

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth differentiation mitotic cycle and oncogenic transformation. This PTP contains an extracellular domain a single transmembrane segment and two tandem intracytoplasmic catalytic domains and thus belongs to receptor type PTP. This gene is specifically expressed in hematopoietic cells. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases and thus functions as a regulator of cytokine receptor signaling. Four alternatively spliced transcripts variants of this gene which encode distinct isoforms have been reported. [provided by RefSeq Jul 2008]

Gene Symbol:   PTPRC
Gene Name:   protein tyrosine phosphatase, receptor type, C
Aliases:   B220, CD45, CD45R, GP180, L-CA, LCA, LY5, T200
RefSeq:   NC_000001.10 NG_007730.1 NT_004487.19 NW_003315907.1
Ensembl:   ENSG00000081237
Entrez:   5788
UniGene:   Hs.654514
Chromosome Mapping:   1q31-q32

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