PrimePCR™ ddPCR™ Expression EvaGreen® Assay: UGT1A4, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0038863; exonic

List Price:    $138.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5006719
Chromosome Location:   2:234627806-234627928question
Amplicon Length:   93

Gene Information

This gene encodes a UDP-glucuronosyltransferase an enzyme of the glucuronidation pathway that transforms small lipophilic molecules such as steroids bilirubin hormones and drugs into water-soluble excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site and is regulated by its own promoter. This enzyme has some glucuronidase activity towards bilirubin although is is more active on amines steroids and sapogenins. [provided by RefSeq Jul 2008]

Gene Symbol:   UGT1A4
Gene Name:   UDP glucuronosyltransferase 1 family, polypeptide A4
Aliases:   HUG-BR2, UDPGT, UDPGT 1-4, UGT1D
RefSeq:   NC_000002.11 NG_002601.2 NG_009254.1 NT_005120.16
Ensembl:   ENSG00000244474
Entrez:   54657
UniGene:   Not Available
Chromosome Mapping:   2q37

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