PrimePCR™ ddPCR™ Expression EvaGreen® Assay: ERG, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0038860; exonic

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5006716
Chromosome Location:   21:39795332-39795428question
Amplicon Length:   67

Gene Information

This gene encodes a member of the erythroblast transformation-specific (ETS) family of transcriptions factors. All members of this family are key regulators of embryonic development cell proliferation differentiation angiogenesis inflammation and apoptosis. The protein encoded by this gene is mainly expressed in the nucleus. It contains an ETS DNA-binding domain and a PNT (pointed) domain which is implicated in the self-association of chimeric oncoproteins. This protein is required for platelet adhesion to the subendothelium inducing vascular cell remodeling. It also regulates hematopoesis and the differentiation and maturation of megakaryocytic cells. This gene is involved in chromosomal translocations resulting in different fusion gene products such as TMPSSR2-ERG and NDRG1-ERG in prostate cancer EWS-ERG in Ewing's sarcoma and FUS-ERG in acute myeloid leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq Jan 2012]

Gene Symbol:   ERG
Gene Name:   v-ets erythroblastosis virus E26 oncogene homolog (avian)
Aliases:   erg-3, p55
RefSeq:   NC_000021.8 NT_011512.11
Ensembl:   ENSG00000157554
Entrez:   2078
UniGene:   Hs.473819
Chromosome Mapping:   21q22.3

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