PrimePCR™ ddPCR™ Expression EvaGreen® Assay: BAG4, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0038849; exonic

List Price:    $130.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5006706
Chromosome Location:   8:38065132-38065244question
Amplicon Length:   83

Gene Information

The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2 Raf-protein kinase steroid hormone receptors growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus which could bind and inhibit the chaperone activity of Hsc70/Hsp70. This protein was found to be associated with the death domain of tumor necrosis factor receptor type 1 (TNF-R1) and death receptor-3 (DR3) and thereby negatively regulates downstream cell death signaling. The regulatory role of this protein in cell death was demonstrated in epithelial cells which undergo apoptosis while integrin mediated matrix contacts are lost. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq Mar 2011]

Gene Symbol:   BAG4
Gene Name:   BCL2-associated athanogene 4
Aliases:   BAG-4, DKFZp586O2022, SODD
RefSeq:   NC_000008.10 NT_167187.1
Ensembl:   ENSG00000156735
Entrez:   9530
UniGene:   Hs.194726
Chromosome Mapping:   8p11.23

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